Prednisone is an oral corticosteroid. It's taken by mouth by adults and children to treat health conditions related to an overactive immune system or inflammation, such as allergies and certain skin conditions. Your healthcare team will determine your dose based on what medical condition you have. Some of the common short-term side effects of prednisone include stomach irritation and mood. Prednisone is a glucocorticoid medication mostly used to suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. [3] It is also used to treat high blood calcium due to cancer and adrenal insufficiency along with other corticosteroids. [3] It is taken by mouth. [3] Common side effects may include cataracts, bone loss, easy bruising. Prednisone is a steroid medication that treats a wide range of health conditions. Find out more about its uses and side effects. Prednisone and other corticosteroids Weigh the benefits and risks of corticosteroids, such as prednisone, when choosing a medicine. Prednisone is a corticosteroid, a type of steroid. Prednisone reduces inflammation and allergy symptoms like those caused by rheumatoid arthritis and allergic asthma. Prednisone modifies the immune response of your body to various medical conditions to minimize inflammation, rashes, swelling and allergic reactions. Find patient medical information for Prednisone (Deltasone, Sterapred, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Prednisone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions. This medicine is available only with your doctor's prescription. Prednisone has been on the market for more than 70 years but is still one of the most commonly prescribed anti-inflammatory or immunosuppressive medications. Prednisone is used to treat dozens of different conditions such as skin disorders, breathing disorders, allergies, arthritis, and ulcerative colitis. But did you know it also has some pretty serious side effects as well? 1. What Is. Prednisone is used to treat allergic disorders, ulcerative colitis, psoriasis and arthritis. Learn about side effects, interactions and indications.